Unrooting the Potential of Intranasal Administration of Curcumin as a Novel Asthma Controller by Alleviating Airway Inflammation

Asthma is a chronic disease where air passage of the lung inflamed and swollen. It among major non-communicable diseases (NCDs) with more than 339 million sufferers affects patients’ quality life. Some drugs are currently used to control asthma symptoms, but it has its own economic burden. The aim this literature review assess potential use curcumin asthma, as cheaper widely available in Indonesia. A total eight was acquired after searching through Pubmed, Clinical Key, Scopus, Science Direct, Proquest, Wiley Online databases keywords including “intranasal”, “curcumin”, “asthma”, “inflammation”, “airway”. Since inflammation most featured phenomenon asthmatics that may lead airway obstruction, important lessen thus asthma. This mechanism can be seen administration curcumin, which although having wide array interaction pathways, showcased have anti-inflammatory effect beneficial also negates other pathologic events relevant appears preventive if administered before exacerbation. Intranasal displayed efficacious model, bested efficacy standard drugs. Lastly, no toxicity observed by included studies.